You cannot rid yourself of mice without understanding the little furry beasts. They are a pack driven society, and can have many requirements to survival. Of course, they need food and water, a place to live and some special needs like a material to chew.
If your home was a large Plexiglas aquarium, you would have no mice. They are not built into your home, and will need a reason to enter. Building your rodent knowledge, and strategies on rodent control, you are empowered here to bring yourself forward with the best solution. Mice are an intelligent species, and as such, should be respected.
If you are afraid of the little buggers, don’t feel bad. They can make you jump in your spot, trigger your stress hormones, as they are a serious threat to human habitation. You are merely reacting to years of evolutionary reflexes, as wild mice have always been a threat to our existence. The Bubonic plague was carried by mice and rodents!